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shinyButchR: Decompose Data with Non-negative Matrix Factorization

★ ★ ★ ★ ☆ | 1 reviews | 3 users

Last accessed Apr 04, 2025
data analysis decompose
Author Ayla Navarro Data Scientist
View Application Download code

About the app

ShinyButchR is an interactive R/Shiny app to perform NMF on an input matrix.Non-negative matrix factorization (NMF) has been widely used for the analysis of genomic data to perform feature extraction and signature identification due to the interpretability of the decomposed signatures. ShinyButchR uses {ButchR} R package to run the matrix decomposition and generate diagnostic plots and visualizations that helps to find association of the NMF signatures to known biological factors. Original publication: Andres Quintero, Daniel Hübschmann, Nils Kurzawa, Sebastian Steinhauser, Philipp Rentzsch, Stephen Krämer, Carolin Andresen, Jeongbin Park, Roland Eils, Matthias Schlesner, Carl Herrmann, ShinyButchR: interactive NMF-based decomposition workflow of genome-scale datasets, Biology Methods and Protocols, bpaa022.

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