organChipSim: Organ-on-a-chip Simulation with Half-life Prediction

★ ☆ ☆ ☆ ☆ | 6 users

Last accessed Oct 19, 2024
Author Sungpil Han Assistant Professor, Catholic University of Korea

About the app

organChipSim is a simulation application offering Organ-on-a-chip simulations with half-life predictions. Known for its aesthetically pleasing interface, organChipSim provides users with an example dataset and the functionality to upload their own datasets. The application allows users to manipulate parameters, observing the effects in various compartments like the liver chip, gut chip, renal system, and plasma. Organ-on-a-chip refers to a microfluidic cell culture device that simulates the activities, mechanics, and physiological responses of entire organs. Pharmacokinetic simulation involves modeling the processes of drug absorption, distribution, metabolism, and excretion in the body. The pharmacokinetic half-life of a drug is the time it takes for half of the drug to be eliminated from the body. In the context of organChipSim, these concepts come together to provide a powerful tool for simulating and predicting drug behavior in a simulated organ-on-a-chip

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